Our Technologies

 

We are powering the next generation of point-of-care diagnostic tools 

Using our patented technology, Nanophage Technologies Ltd design and synthesize custom nano-scale phage particles for diagnostic tools aimed at identifying molecules of interest with high sensitivity for fast, accurate, and early diagnosis. Our technology is applicable to a wide variety of environmental, agricultural, food and medical samples.

 

What are Nanorods?

Nanorods are biological nanoparticles derived from filamentous phage (viruses that infect bacteria). Our proprietary technology allows us to efficiently produce small, non-infectious, highly customizable Nanorods (“Nanophage”).

What we do

By utilizing Nanorods, we create nanoscale scaffolds for housing the detector component of a test (be it an antibody, enzyme or other specific molecule for your target) and providing multiple copies of the sensor molecule (fluorophore, chromophore, or enzyme).

Our system allows for multiple copies the detector component added to the end of the nanorod, and hundreds of copies of the sensor molecule along the length of the nanorod.

The end product is a fully customizable particle that combines the specificity of traditional antibodies with the ability to massively scale-up the signal per-molecule, resulting in highly sensitive, specific detection!

Advantages of Nanorods

Our Nanorods provide the following advantages over traditional antibodies:

  • Enhanced sensitivity: More sensor molecules per detected analyte means greater sensitivity

  • Fully customisable: Option to display antibodies recombinantly or attach them post-production, along with the user's choice of sensor molecule (fluorophore, chromophore or enzyme)

  • Highly versatile: Nanorods can be used in a wide range of applications, from lab-based research to forming the core detection component of advanced diagnostics

  • Scalable: Nanorods are produced using bacterial bioreactors, allowing easy scale-up of production

  • Economic: No expensive cell cultures or complicated technology required for production

  • Green: No inorganic or toxic chemicals are required for Nanorod production

 The applications for Nanorods

We are currently validating our Nanorods for use in the following applications:

Fluorescent Nanorods for flow cytometry, fluorescence microscopy

Enzyme-labelled Nanorods for ELISA, immunohistochemistry

Contact us to learn more

Highly-sensitive Nanorods for advanced custom diagnostics

Check out our cryo-electron microscopy of the f1 filamentous phage article here!