Our Technologies
Nanophage Technologies has developed a novel biological Nanorod platform to revolutionize detection
What are Nanorods?
Nanorods are biological nanoparticles derived from filamentous phage (viruses that infect bacteria). Our proprietary technology allows us to efficiently produce small, non-infectious, highly customizable Nanorods (“Nanophage”).
What we do
By utilizing Nanorods, we create nanoscale scaffolds for attachment of chemicals and biomolecules.
Our system allows for attachment of hundreds of copies of molecules (eg. fluorophores) along the length of the nanorod structure, while the end proteins of the nanorod are available for recombinant expression or chemical conjugation (eg. IgG antibodies).
The end product is a fully customizable particle that combines the specificity of traditional antibodies with the ability to massively scale-up the signal per-molecule, resulting in highly sensitive, specific detection.
Our biological Nanorod platform boosts your assay signals
Fully customizable platform
Produced recombinantly in E. coli
Enhance detection and sensitivity
Key publications
Rakonjac, J., Quezada, R. L., Davenport, C., Van Hung Le, V., Khanum, S., Gonzalez-Miro, M., Zhou, J., Bisset, S., Rajic, M., & Limited, M. V. (2022, February 21). WO2023156985A1 - Production of biological scalable nanorods - Google Patents. https://patents.google.com/patent/WO2023156985A1/en
Rakonjac, J., Gold, V. A., León-Quezada, R. I., & Davenport, C. H. (2024). Structure, biology, and applications of filamentous bacteriophages. Cold Spring Harbor Protocols, 2024(8), pdb-over107754.
Conners, R., León-Quezada, R. I., McLaren, M., Bennett, N. J., Daum, B., Rakonjac, J., & Gold, V. A. (2023). Cryo-electron microscopy of the f1 filamentous phage reveals insights into viral infection and assembly. Nature Communications, 14(1), 2724.
Sattar, S., Bennett, N. J., Wen, W. X., Guthrie, J. M., Blackwell, L. F., Conway, J. F., & Rakonjac, J. (2015). Ff-nano, short functionalized nanorods derived from Ff (f1, fd, or M13) filamentous bacteriophage. Frontiers in microbiology, 6, 316.